CATH Classification

Domain Context

CATH Clusters

Superfamily Transcriptional coactivator/pterin dehydratase
Functional Family Pterin-4-alpha-carbinolamine dehydratase 2

Enzyme Information

4.2.1.96
4a-hydroxytetrahydrobiopterin dehydratase.
based on mapping to UniProt Q9H0N5
(6R)-6-(L-erythro-1,2-dihydroxypropyl)-5,6,7,8-tetrahydro- 4a-hydroxypterin = (6R)-6-(L-erythro-1,2-dihydroxypropyl)-7,8-dihydro- 6H-pterin + H(2)O.
-!- Catalyzes the dehydration of 4a-hydroxytetrahydrobiopterins.

UniProtKB Entries (1)

Q9H0N5
PHS2_HUMAN
Homo sapiens
Pterin-4-alpha-carbinolamine dehydratase 2

PDB Structure

PDB 4C45
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal Structure of Human Pterin-4-Alpha- Carbinolamine Dehydratase 2 (Pcbd2)
Kopec, J., Kiyani, W., Vollmar, M., Shrestha, L., Canning, P., von Delft, F., Burgess-Brown, N., Bountra, C., Arrowsmith, C.H., Edwards, A., Yue, W.W.
To be Published
CATH-Gene3D is a Global Biodata Core Resource Learn more...