CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
2 | Mainly Beta |
|
2.60 | Sandwich |
|
2.60.120 | Jelly Rolls |
|
2.60.120.200 |
Domain Context
CATH Clusters
| Superfamily | 2.60.120.200 |
| Functional Family | Sialidase A |
Enzyme Information
| 3.2.1.18 |
Exo-alpha-sialidase.
based on mapping to UniProt P62575
Hydrolysis of alpha-(2->3)-, alpha-(2->6)-, alpha-(2->8)- glycosidic linkages of terminal sialic acid residues in oligosaccharides, glycoproteins, glycolipids, colominic acid and synthetic substrates.
-!- The enzyme does not act on 4-O-acetylated sialic acids. -!- An endo-alpha-sialidase activity is listed as EC 3.2.1.129. -!- See also EC 4.2.2.15.
|
UniProtKB Entries (1)
| P62575 |
NANA_STREE
Streptococcus pneumoniae
Sialidase A
|
PDB Structure
| PDB | 4C1X |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Structural Characterization of the Carbohydrate-Binding Module of Nana Sialidase, a Pneumococcal Virulence Factor.
Bmc Struct.Biol.
|
