CATH Domain 4bvxA01

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.30	Glutaredoxin
	3.40.30.10	Glutaredoxin

Domain Context

CATH Clusters

Superfamily	Glutaredoxin
Functional Family	methionine--tRNA ligase, cytoplasmic

Enzyme Information

6.1.1.10

Methionine--tRNA ligase.

based on mapping to UniProt P56192

ATP + L-methionine + tRNA(Met) = AMP + diphosphate + L-methionyl- tRNA(Met).

-!- In those organisms producing N-formylmethionyl-tRNA(fMet) for translation initiation, this enzyme also recognizes the initiator tRNA(fMet) and catalyzes the formation of L-methionyl-tRNA(fMet), the substrate for EC 2.1.2.9.

UniProtKB Entries (1)

O43324

MCA3_HUMAN

Homo sapiens

Eukaryotic translation elongation factor 1 epsilon-1

PDB Structure

PDB	4BVX
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Assembly of Multi-tRNA Synthetase Complex Via Heterotetrameric Glutathione Transferase-Homology Domains. Cho, H.Y., Maeng, S.J., Cho, H.J., Choi, Y.S., Chung, J.M., Lee, S., Kim, H.K., Kim, J.H., Eom, C., Kim, Y., Guo, M., Jung, H.S., Kang, B.S., Kim, S. J.Biol.Chem.