CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.30 | 2-Layer Sandwich |
|
3.30.1330 | 60s Ribosomal Protein L30; Chain: A; |
|
3.30.1330.170 | Cyanuric acid hydrolase/Barbiturase, RU A |
Domain Context
CATH Clusters
| Superfamily | Cyanuric acid hydrolase/Barbiturase, RU A |
| Functional Family |
Enzyme Information
| 3.5.2.15 |
Cyanuric acid amidohydrolase.
based on mapping to UniProt P58329
Cyanuric acid + H(2)O = biuret + CO(2).
-!- Along with EC 3.5.1.54 and EC 3.5.1.84, forms part of the cyanuric- acid metabolism pathway, which degrades s-triazide herbicides, such as atrazine (2-chloro-4-(ethylamino)-6-(isopropylamino)-1,3,5- triazine), in bacteria. -!- A key enzyme in the pathway, catalyzing the ring cleavage of cyanuric acid. -!- Specific for cyanuric acid as substrate as neither the structurally related compounds ammeline (2,4-diamino-6-hydroxy-s-triazine) and ammelide (2-amino-4,6-dihydroxy-s-triazine) nor a number of pyrimidine compounds, such as uracil and cytosine, can act as substrates.
|
UniProtKB Entries (1)
| P58329 |
CAH_PSESD
Pseudomonas sp. ADP
Cyanuric acid amidohydrolase
|
PDB Structure
| PDB | 4BVQ |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Cyanuric Acid Hydrolase: Evolutionary Innovation by Structural Concatenation.
Mol.Microbiol.
|
