CATH Domain 4bloA01

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.50	Rossmann fold
	3.40.50.300	P-loop containing nucleotide triphosphate hydrolases

Domain Context

CATH Clusters

Superfamily	P-loop containing nucleotide triphosphate hydrolases
Functional Family	Packaging enzyme P4

Enzyme Information

3.6.1.15

Nucleoside-triphosphate phosphatase.

based on mapping to UniProt P11125

NTP + H(2)O = NDP + phosphate.

-!- The enzyme is found in eukaryotes and thermophilic bacteria, but appears to be absent from mesophilic bacteria. -!- Also hydrolyzes nucleoside diphosphates, thiamine diphosphate and FAD. -!- The enzyme from the plant Pisum sativum (garden pea) is regulated by calmodulin.

UniProtKB Entries (1)

P11125

P4_BPPH6

Pseudomonas virus phi6

Packaging enzyme P4

PDB Structure

PDB	4BLO
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Tracking in Atomic Detail the Functional Specializations in Viral Reca Helicases that Occur During Evolution. El Omari, K., Meier, C., Kainov, D., Sutton, G., Grimes, J.M., Poranen, M.M., Bamford, D.H., Tuma, R., Stuart, D.I., Mancini, E.J. Nucleic Acids Res.