CATH Classification

Domain Context

CATH Clusters

Superfamily Histidine kinase-like ATPase, C-terminal domain
Functional Family Sensor histidine kinase CpxA

Enzyme Information

2.7.13.3
Histidine kinase.
based on mapping to UniProt P0AE82
ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.
-!- This entry has been included to accommodate those protein-histidine kinases for which the phosphorylation site has not been established (i.e. either the pros- or tele-nitrogen of histidine). -!- A number of histones can act as acceptor.

UniProtKB Entries (1)

P0AE82
CPXA_ECOLI
Escherichia coli K-12
Sensor histidine kinase CpxA

PDB Structure

PDB 4BIU
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Segmental Helical Motions and Dynamical Asymmetry Modulate Histidine Kinase Autophosphorylation.
Mechaly, A.E., Sassoon, N., Betton, J.M., Alzari, P.M.
Plos Biol.
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