CATH Domain 4bhiA01

Superfamily	3.30.2020.30
Functional Family	Putative gamma-butyrobetaine dioxygenase

1.14.11.1

Gamma-butyrobetaine dioxygenase.

based on mapping to UniProt O75936

4-trimethylammoniobutanoate + 2-oxoglutarate + O(2) = 3-hydroxy-4- trimethylammoniobutanoate + succinate + CO(2).

BODG_HUMAN

Homo sapiens

Gamma-butyrobetaine dioxygenase

PDB	4BHI
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Targeting Carnitine Biosynthesis: Discovery of New Inhibitors Against Gamma-Butyrobetaine Hydroxylase. Tars, K., Leitans, J., Kazaks, A., Zelencova, D., Liepinsh, E., Kuka, J., Makrecka, M., Lola, D., Andrianovs, V., Gustina, D., Grinberga, S., Liepinsh, E., Kalvinsh, I., Dambrova, M., Loza, E., Pugovics, O. J.Med.Chem.