CATH Domain 4bhfA02

Superfamily	Clavaminate synthase-like
Functional Family	Gamma-butyrobetaine dioxygenase

1.14.11.1

Gamma-butyrobetaine dioxygenase.

based on mapping to UniProt O75936

4-trimethylammoniobutanoate + 2-oxoglutarate + O(2) = 3-hydroxy-4- trimethylammoniobutanoate + succinate + CO(2).

BODG_HUMAN

Homo sapiens

Gamma-butyrobetaine dioxygenase

PDB	4BHF
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Targeting Carnitine Biosynthesis: Discovery of New Inhibitors Against Gamma-Butyrobetaine Hydroxylase. Tars, K., Leitans, J., Kazaks, A., Zelencova, D., Liepinsh, E., Kuka, J., Makrecka, M., Lola, D., Andrianovs, V., Gustina, D., Grinberga, S., Liepinsh, E., Kalvinsh, I., Dambrova, M., Loza, E., Pugovics, O. J.Med.Chem.