CATH Classification

Domain Context

CATH Clusters

Superfamily Calcium-transporting ATPase, cytoplasmic transduction domain A
Functional Family Copper-exporting P-type ATPase A

Enzyme Information

7.2.2.8
P-type Cu(+) transporter.
based on mapping to UniProt Q5ZWR1
ATP + H(2)O + Cu(+)(Side 1) = ADP + phosphate + Cu(+)(Side 2).
-!- A P-type ATPase that undergoes covalent phosphorylation during the transport cycle. -!- This enzyme transports Cu(+) or Ag(+), and cannot transport the divalent ions, contrary to EC 7.2.2.9, which mainly transports the divalent copper ion. -!- Formerly EC 3.6.3.54.

UniProtKB Entries (1)

Q5ZWR1
COPA_LEGPH
Legionella pneumophila subsp. pneumophila str. Philadelphia 1
Copper-exporting P-type ATPase

PDB Structure

PDB 4BEV
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
ATPase Crystal Structure with Bound Phosphate Analogue
Mattle, D., Drachmann, N.D., Liu, X.Y., Gourdon, P., Pedersen, B.P., Morth, P., Wang, J., Nissen, P.
To be Published