CATH Classification

Domain Context

CATH Clusters

Superfamily P-loop containing nucleotide triphosphate hydrolases
Functional Family Dynamin-1-like protein isoform 1

Enzyme Information

3.6.5.5
Dynamin GTPase.
based on mapping to UniProt O00429
GTP + H(2)O = GDP + phosphate.
-!- An enzyme with a molecular mass of about 100 kDa that is involved in endocytosis and is instrumental in pinching off membrane vesicles. -!- Formerly EC 3.6.1.50.

UniProtKB Entries (1)

O00429
DNM1L_HUMAN
Homo sapiens
Dynamin-1-like protein

PDB Structure

PDB 4BEJ
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structural Insights Into Oligomerization and Mitochondrial Remodelling of Dynamin 1-Like Protein.
Frohlich, C., Grabiger, S., Schwefel, D., Faelber, K., Rosenbaum, E., Mears, J., Rocks, O., Daumke, O.
Embo J.
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