CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
2 | Mainly Beta |
|
2.10 | Ribbon |
|
2.10.25 | Laminin |
|
2.10.25.10 | Laminin |
Domain Context
CATH Clusters
| Superfamily | Laminin |
| Functional Family | hepatocyte growth factor activator |
Enzyme Information
| 3.4.21.38 |
Coagulation factor XIIa.
based on mapping to UniProt P00748
Selective cleavage of Arg-|-Ile bonds in factor VII to form factor VIIa and factor XI to form factor XIa.
-!- Also activates plasma prekallikrein and plasminogen. -!- Formed from the proenzyme, factor XII, by plasma kallikrein or factor XIIa. -!- Belongs to peptidase family S1.
|
UniProtKB Entries (1)
| P00748 |
FA12_HUMAN
Homo sapiens
Coagulation factor XII
|
PDB Structure
| PDB | 4BDW |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
The Structure of the Fni-Egf-Like Tandem Domain of Coagulation Factor Xii Solved Using Siras.
Acta Crystallogr.,Sect.F
|
