CATH Domain 4ba0A02

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.20	Alpha-Beta Barrel
	3.20.20	TIM Barrel
	3.20.20.80	Glycosidases

Domain Context

CATH Clusters

Superfamily	Glycosidases
Functional Family	Oligosaccharide 4-alpha-D-glucosyltransferase

Enzyme Information

2.4.1.161

Oligosaccharide 4-alpha-D-glucosyltransferase.

based on mapping to UniProt B3PEE6

Transfers the non-reducing terminal alpha-D-glucose residue from a (1->4)-alpha-D-glucan to the 4-position of a free glucose or of a glucosyl residue at the non-reducing terminus of a (1->4)-alpha-D-glucan, thus bringing about the rearrangement of oligosaccharides.

-!- The enzyme acts on amylose, amylopectin, glycogen and maltooligosaccharides. -!- No detectable free glucose is formed, indicating the enzyme does not act as a hydrolase. -!- The enzyme from the bacterium Cellvibrio japonicus has the highest activity with maltotriose as a donor, and also accepts maltose, while the enzyme from amoeba does not accept maltose. -!- Oligosaccharides with 1->6 linkages cannot function as donors, but can act as acceptors. -!- Unlike EC 2.4.1.25, this enzyme can transfer only a single glucosyl residue.

UniProtKB Entries (1)

B3PEE6

OL4AG_CELJU

Cellvibrio japonicus Ueda107

Oligosaccharide 4-alpha-D-glucosyltransferase

PDB Structure

PDB	4BA0
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Structural Enzymology of Cellvibrio Japonicus Agd31B Reveals Alpha-Transglucosylase Activity in Glycoside Hydrolase Family 31 Larsbrink, J., Izumi, A., Hemsworth, G.R., Davies, G.J., Brumer, H. J.Biol.Chem.