CATH Classification
Level | CATH Code | Description |
---|---|---|
3 | Alpha Beta | |
3.30 | 2-Layer Sandwich | |
3.30.1110 | Adenosine kinase, small domain | |
3.30.1110.20 |
Domain Context
CATH Clusters
Superfamily | 3.30.1110.20 |
Functional Family |
Enzyme Information
2.7.1.147 |
ADP-specific glucokinase.
based on mapping to UniProt Q7M537
ADP + D-glucose = AMP + D-glucose 6-phosphate.
-!- The enzyme from Pyrococcus furiosus is highly specific for D-glucose; there is some activity with 2-deoxy-D-glucose, but no activity with D-fructose, D-mannose or D-galactose as the substrate. -!- No activity is detected when ADP is replaced by ATP, GDP, phosphoenolpyruvate, diphosphate or polyphosphate.
|
UniProtKB Entries (1)
Q7M537 |
GLKA_THELN
Thermococcus litoralis DSM 5473
ADP-dependent glucokinase
|
PDB Structure
PDB | 4B8S |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
Crystal Structure, Saxs and Kinetic Mechanism of Hyperthermophilic Adp-Dependent Glucokinase from Thermococcus Litoralis Reveal a Conserved Mechanism for Catalysis.
Plos One
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