CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.720 | NAD(P)-binding Rossmann-like Domain |
Domain Context
CATH Clusters
| Superfamily | NAD(P)-binding Rossmann-like Domain |
| Functional Family | Bifunctional protein FolD |
Enzyme Information
| 3.5.4.9 |
Methenyltetrahydrofolate cyclohydrolase.
based on mapping to UniProt D0CBC8
5,10-methenyltetrahydrofolate + H(2)O = 10-formyltetrahydrofolate.
|
| 1.5.1.5 |
Methylenetetrahydrofolate dehydrogenase (NADP(+)).
based on mapping to UniProt D0CBC8
5,10-methylenetetrahydrofolate + NADP(+) = 5,10- methenyltetrahydrofolate + NADPH.
|
UniProtKB Entries (1)
| D0CBC8 |
D0CBC8_ACIB2
Acinetobacter baumannii ATCC 19606 = CIP 70.34 = JCM 6841
Bifunctional protein FolD
|
PDB Structure
| PDB | 4B4W |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Acinetobacter Baumannii Fold Ligand Complexes; Potent Inhibitors of Folate Metabolism and a Re-Evaluation of the Ly374571 Structure.
FEBS J.
|
