CATH Classification

Domain Context

CATH Clusters

Superfamily Vaccinia Virus protein VP39
Functional Family Ribosomal RNA large subunit methyltransferase M

Enzyme Information

2.1.1.186
23S rRNA (cytidine(2498)-2'-O)-methyltransferase.
based on mapping to UniProt P0ADR6
S-adenosyl-L-methionine + cytidine(2498) in 23S rRNA = S-adenosyl-L- homocysteine + 2'-O-methylcytidine(2498) in 23S rRNA.

UniProtKB Entries (1)

P0ADR6
RLMM_ECOLI
Escherichia coli K-12
Ribosomal RNA large subunit methyltransferase M

PDB Structure

PDB 4B17
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal Structure of Rlmm, the 2'O-Ribose Methyltransferase for C2498 of Escherichia Coli 23S Rrna.
Punekar, A.S., Shepherd, T.R., Liljeruhm, J., Forster, A.C., Selmer, M.
Nucleic Acids Res.
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