CATH Classification

Domain Context

CATH Clusters

Superfamily Transferase(Phosphotransferase) domain 1
Functional Family serine/threonine-protein kinase Nek1 isoform X1

Enzyme Information

2.7.11.1
Non-specific serine/threonine protein kinase.
based on mapping to UniProt Q96PY6
ATP + a protein = ADP + a phosphoprotein.
-!- This is a heterogeneous group of serine/threonine protein kinases that do not have an activating compound and are either non-specific or their specificity has not been analyzed to date. -!- Formerly EC 2.7.1.37 and EC 2.7.1.70.

UniProtKB Entries (1)

Q96PY6
NEK1_HUMAN
Homo sapiens
Serine/threonine-protein kinase Nek1

PDB Structure

PDB 4APC
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal Structure of Human Nima-Related Kinase 1
Elkins, J.M., Hanchuk, T.D.M., Lovato, D.V., Basei, F.L., Meirelles, G.V., Kobarg, J., Szklarz, M., Vollmar, M., Mahajan, P., Rellos, P., Zhang, Y., Krojer, T., Pike, A.C.W., Bountra, C., Arrowsmith, C., Edwards, A., Knapp, S.
To be Published