CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.10 | Orthogonal Bundle |
|
1.10.275 | Fumarase C; Chain B, domain 1 |
|
1.10.275.10 | Fumarase/aspartase (N-terminal domain) |
Domain Context
CATH Clusters
| Superfamily | Fumarase/aspartase (N-terminal domain) |
| Functional Family | Fumarate hydratase, mitochondrial |
Enzyme Information
| 4.2.1.2 |
Fumarate hydratase.
based on mapping to UniProt P9WN93
(S)-malate = fumarate + H(2)O.
|
UniProtKB Entries (1)
| P9WN93 |
FUMC_MYCTU
Mycobacterium tuberculosis H37Rv
Fumarate hydratase class II
|
PDB Structure
| PDB | 4APA |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Conformational Changes Upon Ligand Binding in the Essential Class II Fumarase Rv1098C from Mycobacterium Tuberculosis.
FEBS Lett.
|
