CATH Domain 4alhA00

CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.20	Up-down Bundle
	1.20.920	Histone Acetyltransferase; Chain A
	1.20.920.10	Bromodomain-like

Domain Context

CATH Clusters

Superfamily	Bromodomain-like
Functional Family	Bromodomain-containing protein 4

Enzyme Information

UniProtKB Entries (1)

BRD2_HUMAN

Homo sapiens

Bromodomain-containing protein 2

PDB Structure

PDB	4ALH
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Fragment-Based Discovery of Bromodomain Inhibitors Part 2: Optimization of Phenylisoxazole Sulfonamides. Bamborough, P., Diallo, H., Goodacre, J.D., Gordon, L., Lewis, A., Seal, J.T., Wilson, D.M., Woodrow, M.D., Chung, C.W. J.Med.Chem.