CATH Classification

Domain Context

CATH Clusters

Superfamily 1.10.472.130
Functional Family Glutathione S-transferase class-mu 26 kDa isozyme

Enzyme Information

2.5.1.18
Glutathione transferase.
based on mapping to UniProt P08515
RX + glutathione = HX + R-S-glutathione.
-!- A group of enzymes of broad specificity. -!- R may be an aliphatic, aromatic or heterocyclic group; X may be a sulfate, nitrile or halide group. -!- Also catalyzes the addition of aliphatic epoxides and arene oxides to glutathione, the reduction of polyol nitrate by glutathione to polyol and nitrile, certain isomerization reactions and disulfide interchange. -!- Formerly EC 1.8.6.1, EC 2.5.1.12, EC 2.5.1.13, EC 2.5.1.14 and EC 4.4.1.7.

UniProtKB Entries (2)

P08515
GST26_SCHJA
Schistosoma japonicum
Glutathione S-transferase class-mu 26 kDa isozyme
P36022
DYHC_YEAST
Saccharomyces cerevisiae S288C
Dynein heavy chain, cytoplasmic

PDB Structure

PDB 4AKG
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Insights Into Dynein Motor Domain Function from a 3.3 Angstrom Crystal Structure
Schmidt, H., Gleave, E.S., Carter, A.P.
Nat.Struct.Mol.Biol.