CATH Classification
Level | CATH Code | Description |
---|---|---|
1 | Mainly Alpha | |
1.10 | Orthogonal Bundle | |
1.10.472 | Cyclin A; domain 1 | |
1.10.472.130 | Dynein motor, AAA2 domain, small subdomain |
Domain Context
CATH Clusters
Superfamily | 1.10.472.130 |
Functional Family | Glutathione S-transferase class-mu 26 kDa isozyme |
Enzyme Information
2.5.1.18 |
Glutathione transferase.
based on mapping to UniProt P08515
RX + glutathione = HX + R-S-glutathione.
-!- A group of enzymes of broad specificity. -!- R may be an aliphatic, aromatic or heterocyclic group; X may be a sulfate, nitrile or halide group. -!- Also catalyzes the addition of aliphatic epoxides and arene oxides to glutathione, the reduction of polyol nitrate by glutathione to polyol and nitrile, certain isomerization reactions and disulfide interchange. -!- Formerly EC 1.8.6.1, EC 2.5.1.12, EC 2.5.1.13, EC 2.5.1.14 and EC 4.4.1.7.
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UniProtKB Entries (2)
P08515 |
GST26_SCHJA
Schistosoma japonicum
Glutathione S-transferase class-mu 26 kDa isozyme
|
P36022 |
DYHC_YEAST
Saccharomyces cerevisiae S288C
Dynein heavy chain, cytoplasmic
|
PDB Structure
PDB | 4AKG |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
Insights Into Dynein Motor Domain Function from a 3.3 Angstrom Crystal Structure
Nat.Struct.Mol.Biol.
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