CATH Classification

Domain Context

CATH Clusters

Superfamily Fumarase/aspartase (C-terminal domain)
Functional Family Fumarate hydratase class II

Enzyme Information

4.2.1.2
Fumarate hydratase.
based on mapping to UniProt P9WN93
(S)-malate = fumarate + H(2)O.

UniProtKB Entries (1)

P9WN93
FUMC_MYCTU
Mycobacterium tuberculosis H37Rv
Fumarate hydratase class II

PDB Structure

PDB 4ADM
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Conformational Changes Upon Ligand Binding in the Essential Class II Fumarase Rv1098C from Mycobacterium Tuberculosis.
Mechaly, A.E., Haouz, A., Miras, I., Barilone, N., Weber, P., Shepard, W., Alzari, P.M., Bellinzoni, M.
FEBS Lett.