CATH Classification

Domain Context

CATH Clusters

Superfamily 3.90.70.100
Functional Family

Enzyme Information

2.7.7.48
RNA-directed RNA polymerase.
based on mapping to UniProt P10358
Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1).
-!- Catalyzes RNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. -!- Can initiate a chain de novo. -!- See also EC 2.7.7.6.
2.1.1.-
Methyltransferases.
based on mapping to UniProt P10358
3.6.4.-
Acting on ATP; involved in cellular and subcellular movement.
based on mapping to UniProt P10358
3.4.22.-
Cysteine endopeptidases.
based on mapping to UniProt P10358

UniProtKB Entries (1)

P10358
POLR_TYMV
Turnip yellow mosaic virus
RNA replicase polyprotein

PDB Structure

PDB 4A5U
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
A Compact Viral Processing Proteinase/Ubiquitin Hydrolase from the Otu Family.
Lombardi, C., Ayach, M., Beaurepaire, L., Chenon, M., Andreani, J., Guerois, R., Jupin, I., Bressanelli, S.
Plos Pathog.
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