CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.50 | 3-Layer(bba) Sandwich |
|
3.50.4 | Hepatocyte Growth Factor |
|
3.50.4.10 | Hepatocyte Growth Factor |
Domain Context
CATH Clusters
| Superfamily | Hepatocyte Growth Factor |
| Functional Family | Plasminogen |
Enzyme Information
| 3.4.21.7 |
Plasmin.
based on mapping to UniProt P00747
Preferential cleavage: Lys-|-Xaa > Arg-|-Xaa, higher selectivity than trypsin. Converts fibrin into soluble products.
-!- Formed from plasminogen by proteolysis which results in multiple forms of the active plasmin. -!- Belongs to peptidase family S1. -!- Formerly EC 3.4.4.14.
|
UniProtKB Entries (1)
| P00747 |
PLMN_HUMAN
Homo sapiens
Plasminogen
|
PDB Structure
| PDB | 4A5T |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Crystal Structure of the Native Plasminogen Reveals an Activation-Resistant Compact Conformation.
J. Thromb. Haemost.
|
