CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.90 | Alpha-Beta Complex |
|
3.90.1150 | Aspartate Aminotransferase, domain 1 |
|
3.90.1150.10 | Aspartate Aminotransferase, domain 1 |
Domain Context
CATH Clusters
| Superfamily | Aspartate Aminotransferase, domain 1 |
| Functional Family | Bifunctional dethiobiotin synthetase/7,8-diamino-pelargonic acid aminotransferase, mitochondrial |
Enzyme Information
| 6.3.3.3 |
Dethiobiotin synthase.
based on mapping to UniProt B0F481
ATP + 7,8-diaminononanoate + CO(2) = ADP + phosphate + dethiobiotin.
-!- CTP has half the activity of ATP.
|
| 2.6.1.62 |
Adenosylmethionine--8-amino-7-oxononanoate transaminase.
based on mapping to UniProt B0F481
S-adenosyl-L-methionine + 8-amino-7-oxononanoate = S-adenosyl-4- methylthio-2-oxobutanoate + 7,8-diaminononanoate.
-!- S-adenosylhomocysteine can also act as donor.
|
UniProtKB Entries (1)
| B0F481 |
BIODA_ARATH
Arabidopsis thaliana
Bifunctional dethiobiotin synthetase/7,8-diamino-pelargonic acid aminotransferase, mitochondrial
|
PDB Structure
| PDB | 4A0F |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Biochemical and Structural Characterization of the Arabidopsis Bifunctional Enzyme Dethiobiotin Synthetase-Diaminopelargonic Acid Aminotransferase: Evidence for Substrate Channeling in Biotin Synthesis.
Plant Cell
|
