CATH Classification

Domain Context

CATH Clusters

Superfamily Phosphorylase Kinase; domain 1
Functional Family 3-phosphoinositide-dependent protein kinase 1

Enzyme Information

2.7.11.1
Non-specific serine/threonine protein kinase.
based on mapping to UniProt O15530
ATP + a protein = ADP + a phosphoprotein.
-!- This is a heterogeneous group of serine/threonine protein kinases that do not have an activating compound and are either non-specific or their specificity has not been analyzed to date. -!- Formerly EC 2.7.1.37 and EC 2.7.1.70.

UniProtKB Entries (1)

O15530
PDPK1_HUMAN
Homo sapiens
3-phosphoinositide-dependent protein kinase 1

PDB Structure

PDB 4A06
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Allosteric Regulation of Protein Kinase Pkczeta by the N-Terminal C1 Domain and Small Compounds to the Pif-Pocket.
Lopez-Garcia, L.A., Schulze, J.O., Frohner, W., Zhang, H., Suss, E., Weber, N., Navratil, J., Amon, S., Hindie, V., Zeuzem, S., Jorgensen, T.J., Alzari, P.M., Neimanis, S., Engel, M., Biondi, R.M.
Chem.Biol.
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