CATH Domain 3zjuA02

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.50	Rossmann fold
	3.40.50.620	HUPs

Domain Context

CATH Clusters

Superfamily	HUPs
Functional Family	Leucine--tRNA ligase

Enzyme Information

6.1.1.4

Leucine--tRNA ligase.

based on mapping to UniProt P07813

ATP + L-leucine + tRNA(Leu) = AMP + diphosphate + L-leucyl-tRNA(Leu).

UniProtKB Entries (1)

SYL_ECOLI

Escherichia coli K-12

Leucine--tRNA ligase

PDB Structure

PDB	3ZJU
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Discovery of a Novel Class of Boron-Based Antibacterials with Activity Against Gram-Negative Bacteria. Hernandez, V., Crepin, T., Palencia, A., Cusack, S., Akama, T., Baker, S.J., Bu, W., Feng, L., Freund, Y.R., Liu, L., Meewan, M., Mohan, M., Mao, W., Rock, F.L., Sexton, H., Sheoran, A., Zhang, Y., Zhang, Y., Zhou, Y., Nieman, J.A., Anugula, M.R., Keramane, E.M., Savariraj, K., Reddy, D.S., Sharma, R., Subedi, R., Singh, R., O'Leary, A., Simon, N.L., De Marsh, P.L., Mushtaq, S., Warner, M., Livermore, D.M., Alley, M.R.K., Plattner, J.J. Antimicrob.Agents Chemother.