CATH Classification

Domain Context

CATH Clusters

Superfamily Glycosidases
Functional Family Beta-glucosidase 11

Enzyme Information

3.2.1.105
3-alpha-(S)-strictosidine beta-glucosidase.
based on mapping to UniProt Q8GU20
Strictosidine + H(2)O = D-glucose + strictosidine aglycone.
-!- Does not act on a number of closely related glycosides. -!- Strictosidine is a precursor of indole alkaloids.

UniProtKB Entries (1)

Q8GU20
SG1_RAUSE
Rauvolfia serpentina
Strictosidine-O-beta-D-glucosidase

PDB Structure

PDB 3ZJ7
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Ligand Structures of Synthetic Deoxa-Pyranosylamines with Raucaffricine and Strictosidine Glucosidases Provide Structural Insights Into Their Binding and Inhibitory Behaviours.
Xia, L., Lin, H., Staniek, A., Panjikar, S., Ruppert, M., Hilgers, P., Williardt, J., Rajendran, C., Wang, M., Warzecha, H., Jager, V., Stockigt, J.
J.Enzyme.Inhib.Med.Chem.
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