CATH Classification

Domain Context

CATH Clusters

Superfamily Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain
Functional Family Leucine--tRNA ligase

Enzyme Information

6.1.1.4
Leucine--tRNA ligase.
based on mapping to UniProt P07813
ATP + L-leucine + tRNA(Leu) = AMP + diphosphate + L-leucyl-tRNA(Leu).

UniProtKB Entries (1)

P07813
SYL_ECOLI
Escherichia coli K-12
Leucine--tRNA ligase

PDB Structure

PDB 3ZGZ
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Plant Tumour Biocontrol Agent Employs a tRNA-Dependent Mechanism to Inhibit Leucyl-tRNA Synthetase
Chopra, S., Palencia, A., Virus, C., Tripathy, A., Temple, B.R., Velazquez-Campoy, A., Cusack, S., Reader, J.S.
Nat.Commun.