CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.1100 |
Domain Context
CATH Clusters
| Superfamily | 3.40.50.1100 |
| Functional Family | Cystathionine beta-synthase |
Enzyme Information
| 2.6.99.3 |
O-ureido-L-serine synthase.
based on mapping to UniProt D2Z027
O-acetyl-L-serine + hydroxyurea = O-ureido-L-serine + acetate.
-!- The enzyme participates in the biosynthetic pathway of D-cycloserine, an antibiotic substance produced by several Streptomyces species. -!- Also catalyzes EC 2.5.1.47.
|
| 2.5.1.47 |
Cysteine synthase.
based on mapping to UniProt D2Z027
O-acetyl-L-serine + hydrogen sulfide = L-cysteine + acetate.
-!- Some alkyl thiols, cyanide, pyrazole and some other heterocyclic compounds can act as acceptors. -!- Not identical with EC 2.5.1.51, EC 2.5.1.52 and EC 2.5.1.53. -!- Formerly EC 4.2.99.8.
|
UniProtKB Entries (1)
| D2Z027 |
DCSD_STRLA
Streptomyces lavendulae
O-ureido-L-serine synthase
|
PDB Structure
| PDB | 3X44 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
The structural and mutational analyses of O-ureido-L-serine synthase necessary for D-cycloserine biosynthesis
Febs J.
|