CATH Classification
Level | CATH Code | Description |
---|---|---|
1 | Mainly Alpha | |
1.10 | Orthogonal Bundle | |
1.10.472 | Cyclin A; domain 1 | |
1.10.472.20 | Nitrile hydratase, beta subunit |
Domain Context
CATH Clusters
Superfamily | Nitrile hydratase, beta subunit |
Functional Family |
Enzyme Information
4.2.1.84 |
Nitrile hydratase.
based on mapping to UniProt P13449
An aliphatic amide = a nitrile + H(2)O.
-!- Acts on short-chain aliphatic nitriles, converting them into the corresponding acid amides. -!- Does not act on these amides or on aromatic nitriles (cf. EC 3.5.5.1).
|
UniProtKB Entries (1)
P13449 |
NHAB_RHOER
Rhodococcus erythropolis
Nitrile hydratase subunit beta
|
PDB Structure
PDB | 3X25 |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
Time-Resolved Crystallography of the Reaction Intermediate of Nitrile Hydratase: Revealing a Role for the Cysteinesulfenic Acid Ligand as a Catalytic Nucleophile.
Angew.Chem.Int.Ed.Engl.
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