CATH Classification

Domain Context

CATH Clusters

Superfamily Glutaredoxin
Functional Family Protein disulfide-isomerase

Enzyme Information

5.3.4.1
Protein disulfide-isomerase.
based on mapping to UniProt P55059
Catalyzes the rearrangement of -S-S- bonds in proteins.
-!- Needs reducing agents or partly reduced enzyme; the reaction depends on sulfhydryl-disulfide interchange.

UniProtKB Entries (1)

P55059
PDI_HUMIN
Humicola insolens
Protein disulfide-isomerase

PDB Structure

PDB 3WT2
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Redox-dependent conformational transition of catalytic domain of protein disulfide isomerase indicated by crystal structure-based molecular dynamics simulation
Inagaki, K., Satoh, T., Itoh, S.G., Okumura, H., Kato, K.
Chem.Phys.Lett.