CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
2 | Mainly Beta |
|
2.40 | Beta Barrel |
|
2.40.37 | Lyase, Ornithine Decarboxylase; Chain A, domain 1 |
|
2.40.37.20 | D-serine dehydratase-like domain |
Domain Context
CATH Clusters
| Superfamily | D-serine dehydratase-like domain |
| Functional Family |
Enzyme Information
| 4.3.1.27 |
Threo-3-hydroxy-D-aspartate ammonia-lyase.
based on mapping to UniProt B2DFG5
Threo-3-hydroxy-D-aspartate = oxaloacetate + NH(3).
-!- The enzyme, purified from the bacterium Delftia sp. HT23, also has activity against L-threo-3-hydroxyaspartate, L-erythro-3- hydroxyaspartate, and D-serine. -!- Different from EC 4.3.1.20 and EC 4.3.1.16. -!- Requires a divalent cation such as Mn(2+), Co(2+) or Ni(2+).
|
UniProtKB Entries (1)
| B2DFG5 |
DTHAD_DELSH
Delftia sp. HT23
D-threo-3-hydroxyaspartate dehydratase
|
PDB Structure
| PDB | 3WQG |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Structural insights into the substrate stereospecificity of D-threo-3-hydroxyaspartate dehydratase from Delftia sp. HT23: a useful enzyme for the synthesis of optically pure L-threo- and D-erythro-3-hydroxyaspartate
Appl.Microbiol.Biotechnol.
|
