CATH Classification
Level | CATH Code | Description |
---|---|---|
2 | Mainly Beta | |
2.40 | Beta Barrel | |
2.40.37 | Lyase, Ornithine Decarboxylase; Chain A, domain 1 | |
2.40.37.20 | D-serine dehydratase-like domain |
Domain Context
CATH Clusters
Superfamily | D-serine dehydratase-like domain |
Functional Family |
Enzyme Information
4.3.1.27 |
Threo-3-hydroxy-D-aspartate ammonia-lyase.
based on mapping to UniProt B2DFG5
Threo-3-hydroxy-D-aspartate = oxaloacetate + NH(3).
-!- The enzyme, purified from the bacterium Delftia sp. HT23, also has activity against L-threo-3-hydroxyaspartate, L-erythro-3- hydroxyaspartate, and D-serine. -!- Different from EC 4.3.1.20 and EC 4.3.1.16. -!- Requires a divalent cation such as Mn(2+), Co(2+) or Ni(2+).
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UniProtKB Entries (1)
B2DFG5 |
DTHAD_DELSH
Delftia sp. HT23
D-threo-3-hydroxyaspartate dehydratase
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PDB Structure
PDB | 3WQC |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
Structural insights into the substrate stereospecificity of D-threo-3-hydroxyaspartate dehydratase from Delftia sp. HT23: a useful enzyme for the synthesis of optically pure L-threo- and D-erythro-3-hydroxyaspartate
Appl.Microbiol.Biotechnol.
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