CATH Domain 3whaA00

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.30	2-Layer Sandwich
	3.30.565	Heat Shock Protein 90
	3.30.565.10	Histidine kinase-like ATPase, C-terminal domain

Domain Context

CATH Clusters

Superfamily	Histidine kinase-like ATPase, C-terminal domain
Functional Family	Heat shock protein HSP 90-alpha

Enzyme Information

UniProtKB Entries (1)

HS90A_HUMAN

Homo sapiens

Heat shock protein HSP 90-alpha

PDB Structure

PDB	3WHA
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Design and synthesis of 2-amino-6-(1H,3H-benzo[de]isochromen-6-yl)-1,3,5-triazines as novel Hsp90 inhibitors Suda, A., Kawasaki, K., Komiyama, S., Isshiki, Y., Yoon, D.-O., Kim, S.-J., Na, Y.-J., Hasegawa, K., Fukami, T.A., Sato, S., Miura, T., Ono, N., Yamazaki, T., Saitoh, R., Shimma, N., Shiratori, Y., Tsukuda, T. Bioorg.Med.Chem.