CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.70 | Box |
|
3.70.10 | Proliferating Cell Nuclear Antigen |
|
3.70.10.10 |
Domain Context
CATH Clusters
| Superfamily | 3.70.10.10 |
| Functional Family | Proliferating cell nuclear antigen |
Enzyme Information
UniProtKB Entries (1)
| P12004 |
PCNA_HUMAN
Homo sapiens
Proliferating cell nuclear antigen
|
PDB Structure
| PDB | 3WGW |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
A small molecule inhibitor of monoubiquitinated Proliferating Cell Nuclear Antigen (PCNA) inhibits repair of interstrand DNA cross-link, enhances DNA double strand break, and sensitizes cancer cells to cisplatin.
J.Biol.Chem.
|