CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.20 | Alpha-Beta Barrel |
|
3.20.20 | TIM Barrel |
|
3.20.20.100 | NADP-dependent oxidoreductase domain |
Domain Context
CATH Clusters
| Superfamily | NADP-dependent oxidoreductase domain |
| Functional Family |
Enzyme Information
| 1.1.1.168 |
2-dehydropantolactone reductase (Re-specific).
based on mapping to UniProt Q76L37
(R)-pantolactone + NADP(+) = 2-dehydropantolactone + NADPH.
-!- The enzyme from Saccharomyces cerevisiae differs from that from Escherichia coli (EC 1.1.1.214), which is specific for the Si-face of NADP, and in receptor requirements from EC 1.1.99.26.
|
UniProtKB Entries (1)
| Q76L37 |
CPRC1_CANPA
Candida parapsilosis
NADPH-dependent conjugated polyketone reductase C1
|
PDB Structure
| PDB | 3WG6 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Crystal structure of conjugated polyketone reductase (CPR-C1) from Candida parapsilosis IFO 0708 complexed with NADPH
Proteins
|
