CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.570 | Extracellular Endonuclease; Chain A |
|
3.40.570.10 | Extracellular Endonuclease, subunit A |
Domain Context
CATH Clusters
| Superfamily | Extracellular Endonuclease, subunit A |
| Functional Family | Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 |
Enzyme Information
| 3.1.4.39 |
Alkylglycerophosphoethanolamine phosphodiesterase.
based on mapping to UniProt Q9R1E6
1-alkyl-sn-glycero-3-phosphoethanolamine + H(2)O = 1-alkyl-sn-glycerol 3-phosphate + ethanolamine.
-!- Also acts on acyl and choline analogs.
|
UniProtKB Entries (1)
| Q9R1E6 |
ENPP2_MOUSE
Mus musculus
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2
|
PDB Structure
| PDB | 3WAV |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Screening and X-ray Crystal Structure-based Optimization of Autotaxin (ENPP2) Inhibitors, Using a Newly Developed Fluorescence Probe
Acs Chem.Biol.
|
