CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.30 | Glutaredoxin |
|
3.40.30.10 | Glutaredoxin |
Domain Context
CATH Clusters
| Superfamily | Glutaredoxin |
| Functional Family | protein disulfide-isomerase A6 isoform X1 |
Enzyme Information
| 5.3.4.1 |
Protein disulfide-isomerase.
based on mapping to UniProt Q15084
Catalyzes the rearrangement of -S-S- bonds in proteins.
-!- Needs reducing agents or partly reduced enzyme; the reaction depends on sulfhydryl-disulfide interchange.
|
UniProtKB Entries (2)
| O08807 |
PRDX4_MOUSE
Mus musculus
Peroxiredoxin-4
|
| Q15084 |
PDIA6_HUMAN
Homo sapiens
Protein disulfide-isomerase A6
|
PDB Structure
| PDB | 3W8J |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Synergistic cooperation of PDI family members in peroxiredoxin 4-driven oxidative protein folding
Sci Rep
|
