CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.30 | 2-Layer Sandwich |
|
3.30.160 | Double Stranded RNA Binding Domain |
|
3.30.160.20 |
Domain Context
CATH Clusters
| Superfamily | 3.30.160.20 |
| Functional Family | ATP-dependent RNA helicase A |
Enzyme Information
| 3.6.4.13 |
RNA helicase.
based on mapping to UniProt Q08211
ATP + H(2)O = ADP + phosphate.
-!- RNA helicases utilize the energy from ATP hydrolysis to unwind RNA. -!- Some of them unwind RNA with a 3' to 5' polarity, other show 5' to 3' polarity. -!- Some helicases unwind DNA as well as RNA. -!- May be identical with EC 3.6.4.12 (DNA helicase).
|
UniProtKB Entries (1)
| Q08211 |
DHX9_HUMAN
Homo sapiens
ATP-dependent RNA helicase A
|
PDB Structure
| PDB | 3VYY |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Structural insights into RISC assembly facilitated by dsRNA-binding domains of human RNA helicase A (DHX9)
Nucleic Acids Res.
|
