CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.830 | Protocatechuate 4,5-dioxygenase; Chain B |
|
3.40.830.10 | LigB-like |
Domain Context
CATH Clusters
| Superfamily | LigB-like |
| Functional Family |
Enzyme Information
| 1.13.11.76 |
2-amino-5-chlorophenol 1,6-dioxygenase.
based on mapping to UniProt Q6J1Z6
2-amino-5-chlorophenol + O(2) = 2-amino-5-chloromuconate 6-semialdehyde.
-!- The enzyme, a member of the nonheme-iron(II)-dependent dioxygenase family, is an extradiol-type dioxygenase that utilizes a non-heme ferrous iron to cleave the aromatic ring at the meta position (relative to the hydroxyl substituent). -!- The enzyme from the bacterium Comamonas testosteroni CNB-1 also has the activity of EC 1.3.1.74.
|
| 1.13.11.74 |
2-aminophenol 1,6-dioxygenase.
based on mapping to UniProt Q6J1Z6
2-aminophenol + O(2) = 2-aminomuconate 6-semialdehyde.
-!- The enzyme, is an extradiol-type dioxygenase that utilizes a non-heme ferrous iron to cleave the aromatic ring at the meta position (relative to the hydroxyl substituent). -!- The enzyme also has some activity with 2-amino-5-methylphenol and 2-amino-4-methylphenol. -!- The enzyme from the bacterium Comamonas testosteroni CNB-1 also has the activity of EC 1.13.11.76. -!- Formerly EC 1.13.11.n1.
|
UniProtKB Entries (1)
| Q6J1Z6 |
AMNB_COMTE
Comamonas testosteroni
2-aminophenol 1,6-dioxygenase subunit beta
|
PDB Structure
| PDB | 3VSG |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Structures of aminophenol dioxygenase in complex with intermediate, product and inhibitor
Acta Crystallogr.,Sect.D
|
