CATH Classification

Domain Context

CATH Clusters

Superfamily P-loop containing nucleotide triphosphate hydrolases
Functional Family Cell division control protein 42 homolog

Enzyme Information

UniProtKB Entries (2)

Q8C147
DOCK8_MOUSE
Mus musculus
Dedicator of cytokinesis protein 8
P60953
CDC42_HUMAN
Homo sapiens
Cell division control protein 42 homolog

PDB Structure

PDB 3VHL
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
DOCK8 is a Cdc42 activator critical for interstitial dendritic cell migration during immune responses.
Harada, Y., Tanaka, Y., Terasawa, M., Pieczyk, M., Habiro, K., Katakai, T., Hanawa-Suetsugu, K., Kukimoto-Niino, M., Nishizaki, T., Shirouzu, M., Duan, X., Uruno, T., Nishikimi, A., Sanematsu, F., Yokoyama, S., Stein, J.V., Kinashi, T., Fukui, Y.
Blood