CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.20 | Up-down Bundle |
|
1.20.58 | Methane Monooxygenase Hydroxylase; Chain G, domain 1 |
|
1.20.58.740 | DOCK DHR2 domain, lobe C |
Domain Context
CATH Clusters
| Superfamily | 1.20.58.740 |
| Functional Family | Dedicator of cytokinesis protein 7 |
Enzyme Information
UniProtKB Entries (2)
| Q8C147 |
DOCK8_MOUSE
Mus musculus
Dedicator of cytokinesis protein 8
|
| P60953 |
CDC42_HUMAN
Homo sapiens
Cell division control protein 42 homolog
|
PDB Structure
| PDB | 3VHL |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
DOCK8 is a Cdc42 activator critical for interstitial dendritic cell migration during immune responses.
Blood
|
