CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
2 | Mainly Beta |
|
2.60 | Sandwich |
|
2.60.60 | Lipoxygenase-1 |
|
2.60.60.20 | PLAT/LH2 domain |
Domain Context
CATH Clusters
| Superfamily | PLAT/LH2 domain |
| Functional Family | Arachidonate 5-lipoxygenase a |
Enzyme Information
| 1.13.11.34 |
Arachidonate 5-lipoxygenase.
based on mapping to UniProt P09917
Arachidonate + O(2) = leukotriene A(4) + H(2)O.
|
UniProtKB Entries (1)
| P09917 |
LOX5_HUMAN
Homo sapiens
Arachidonate 5-lipoxygenase
|
PDB Structure
| PDB | 3V99 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Conversion of human 5-lipoxygenase to a 15-lipoxygenase by a point mutation to mimic phosphorylation at Serine-663.
Faseb J.
|
