CATH Domain 3v5wG00

Level	CATH Code	Description
	4	Few Secondary Structures
	4.10	Irregular
	4.10.260	G Protein Gi Gamma 2
	4.10.260.10	Transducin (heterotrimeric G protein), gamma chain

Superfamily	Transducin (heterotrimeric G protein), gamma chain
Functional Family

P63212	GBG2_BOVIN Bos taurus Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2
P25098	ARBK1_HUMAN Homo sapiens Beta-adrenergic receptor kinase 1

PDB	3V5W
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Paroxetine is a direct inhibitor of g protein-coupled receptor kinase 2 and increases myocardial contractility. Thal, D.M., Homan, K.T., Chen, J., Wu, E.K., Hinkle, P.M., Huang, Z.M., Chuprun, J.K., Song, J., Gao, E., Cheung, J.Y., Sklar, L.A., Koch, W.J., Tesmer, J.J. Acs Chem.Biol.