CATH Classification
Level | CATH Code | Description |
---|---|---|
2 | Mainly Beta | |
2.130 | 7 Propeller | |
2.130.10 | Methylamine Dehydrogenase; Chain H | |
2.130.10.10 | YVTN repeat-like/Quinoprotein amine dehydrogenase |
Domain Context
CATH Clusters
Superfamily | YVTN repeat-like/Quinoprotein amine dehydrogenase |
Functional Family | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 |
Enzyme Information
UniProtKB Entries (2)
P63212 |
GBG2_BOVIN
Bos taurus
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2
|
P25098 |
ARBK1_HUMAN
Homo sapiens
Beta-adrenergic receptor kinase 1
|
PDB Structure
PDB | 3V5W |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
Paroxetine is a direct inhibitor of g protein-coupled receptor kinase 2 and increases myocardial contractility.
Acs Chem.Biol.
|