CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.20 | Alpha-Beta Barrel |
|
3.20.20 | TIM Barrel |
|
3.20.20.100 | NADP-dependent oxidoreductase domain |
Domain Context
CATH Clusters
| Superfamily | NADP-dependent oxidoreductase domain |
| Functional Family |
Enzyme Information
| 1.1.1.317 |
Perakine reductase.
based on mapping to UniProt Q3L181
Raucaffrinoline + NADP(+) = perakine + NADPH.
-!- The biosynthesis of raucaffrinoline from perakine is a side route of the ajmaline biosynthesis pathway. -!- The enzyme is a member of the aldo-keto reductase enzyme superfamily from higher plants.
|
UniProtKB Entries (1)
| Q3L181 |
PERR_RAUSE
Rauvolfia serpentina
Perakine reductase
|
PDB Structure
| PDB | 3V0T |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Crystal structure of perakine reductase, founding member of a novel aldo-keto reductase (AKR) subfamily that undergoes unique conformational changes during NADPH binding.
J.Biol.Chem.
|
