CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.20 | Up-down Bundle |
|
1.20.1120 | Clostridium botulinum neurotoxin B, "coiled-coil" domain |
|
1.20.1120.10 | Clostridium botulinum neurotoxin b, "coiled-coil" domain |
Domain Context
CATH Clusters
| Superfamily | Clostridium botulinum neurotoxin b, "coiled-coil" domain |
| Functional Family |
Enzyme Information
| 3.4.24.69 |
Bontoxilysin.
based on mapping to UniProt P0DPI1
Limited hydrolysis of proteins of the neuroexocytosis apparatus, synaptobrevins, SNAP25 or syntaxin. No detected action on small molecule substrates.
-!- Belongs to peptidase family M27.
|
UniProtKB Entries (2)
| P0DPI1 |
BXA1_CLOBH
Clostridium botulinum A str. Hall
Botulinum neurotoxin type A
|
| Q45914 |
BXAN_CLOBO
Clostridium botulinum
Non-toxic nonhemagglutinin type A
|
PDB Structure
| PDB | 3V0A |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Botulinum neurotoxin is shielded by NTNHA in an interlocked complex.
Science
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