CATH Classification
Level | CATH Code | Description |
---|---|---|
3 | Alpha Beta | |
3.30 | 2-Layer Sandwich | |
3.30.505 | SHC Adaptor Protein | |
3.30.505.10 | SH2 domain |
Domain Context
CATH Clusters
Superfamily | SH2 domain |
Functional Family | Tyrosine-protein kinase |
Enzyme Information
2.7.10.2 |
Non-specific protein-tyrosine kinase.
based on mapping to UniProt P00519
ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.
-!- Unlike EC 2.7.10.1, this protein-tyrosine kinase does not have a transmembrane domain. -!- In the human genome, 32 non-specific protein-tyrosine kinases have been identified and these can be divided into 10 families. -!- Formerly EC 2.7.1.112.
|
UniProtKB Entries (1)
P00519 |
ABL1_HUMAN
Homo sapiens
Tyrosine-protein kinase ABL1
|
PDB Structure
PDB | 3UYO |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
Teaching an old scaffold new tricks: monobodies constructed using alternative surfaces of the FN3 scaffold.
J.Mol.Biol.
|