CATH Domain 3umoA00

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.1190	UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase
	3.40.1190.20	Ribokinase

Domain Context

CATH Clusters

Superfamily	3.40.1190.20
Functional Family	Phosphofructokinase

Enzyme Information

2.7.1.11

6-phosphofructokinase.

based on mapping to UniProt P06999

ATP + D-fructose 6-phosphate = ADP + D-fructose 1,6-bisphosphate.

-!- D-tagatose 6-phosphate and sedoheptulose 7-phosphate can act as acceptors. -!- UTP, CTP and ITP can act as donors. -!- Not identical with EC 2.7.1.105.

UniProtKB Entries (1)

P06999

PFKB_ECOLI

Escherichia coli K-12

ATP-dependent 6-phosphofructokinase isozyme 2

PDB Structure

PDB	3UMO
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	A Ribokinase Family Conserved Monovalent Cation Binding Site Enhances the MgATP-induced Inhibition in E. coli Phosphofructokinase-2 Baez, M., Cabrera, R., Pereira, H.M., Blanco, A., Villalobos, P., Ramirez-Sarmiento, C.A., Caniuguir, A., Guixe, V., Garratt, R.C., Babul, J. Biophys.J.