CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
6 | Special |
|
6.10 | Helix non-globular |
|
6.10.250 | Single alpha-helices involved in coiled-coils or other helix-helix interfaces |
|
6.10.250.2210 |
Domain Context
CATH Clusters
| Superfamily | 6.10.250.2210 |
| Functional Family |
Enzyme Information
UniProtKB Entries (1)
| A7UD81 |
A7UD81_PLAFA
Plasmodium falciparum
Bifunctional dihydrofolate reductase-thymidylate synthase
|
PDB Structure
| PDB | 3UM6 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Combined Spatial Limitation around Residues 16 and 108 of Plasmodium falciparum Dihydrofolate Reductase Explains Resistance to Cycloguanil.
Antimicrob.Agents Chemother.
|