CATH Classification

Domain Context

CATH Clusters

Superfamily SH3 Domains
Functional Family Tyrosine-protein kinase Fyn

Enzyme Information

2.7.10.2
Non-specific protein-tyrosine kinase.
based on mapping to UniProt P39688
ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.
-!- Unlike EC 2.7.10.1, this protein-tyrosine kinase does not have a transmembrane domain. -!- In the human genome, 32 non-specific protein-tyrosine kinases have been identified and these can be divided into 10 families. -!- Formerly EC 2.7.1.112.

UniProtKB Entries (1)

P39688
FYN_MOUSE
Mus musculus
Tyrosine-protein kinase Fyn

PDB Structure

PDB 3UF4
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal structure of a SH3 and SH2 domains of FYN protein (Proto-concogene Tyrosine-protein kinase Fyn) from Mus musculus at 1.98 A resolution
Joint Center for Structural Genomics (JCSG), Partnership for T-Cell Biology (TCELL)
To be published
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